Asbestos / Mesothelioma

Rare genetic cause of peritoneal mesothelioma points to targeted therapy

Mesothelioma is a rare and aggressive tumor that, in many cases, results from exposure to asbestos. But over the last several decades, other causes of the disease have emerged, including treatment with high-intensity therapeutic radiation and, more recently, an inherited genetic mutation. Now, through an unexpected observation and a meticulous study of patients seen at […]

Asbestos / Mesothelioma

Mesothelioma shows promising response to existing immunotherapy drug

An existing immunotherapy drug called pembrolizumab appears to be effective in the treatment of malignant pleural mesothelioma, a rare and aggressive lung cancer that is primarily caused by exposure to asbestos. Writing in The Lancet Oncology, researchers describe the first study to show a positive result from using the antibody drug against this rare cancer. […]

Asbestos / Mesothelioma

Active agent from the Caribbean sea cucumber could improve treatment for malignant pleural mesothelioma

Researchers at the Comprehensive Cancer Center of MedUni Vienna and Vienna General Hospital have discovered a new option for treating malignant pleural mesothelioma. For the first time in the world, they were able to show in a preclinical study, both in the cell culture and in the animal model, that trabectedin, a chemotherapy drug that […]

Asbestos / Mesothelioma

Immunotherapy with live bacterium improves response rate in malignant pleural mesothelioma

Immunotherapy with a live bacterium combined with chemotherapy demonstrated more than 90% disease control and 59% response rate in patients with malignant pleural mesothelioma (MPM), according to the results of a phase Ib trial presented today at the European Lung Cancer Conference (ELCC) 2016 in Geneva, Switzerland.1 “Malignant pleural mesothelioma is a cancer of the […]

Asbestos / Mesothelioma

Gene study uncovers ‘spectrum of mutations’ in mesothelioma

A new study identifies previously unknown genetic alterations behind mesothelioma – a rare and deadly cancer whose main cause is exposure to asbestos. The findings include some mutations that may serve as new targets for treatment and others that could help improve the diagnosis, screening and prediction of outcomes for patients. The researchers say knowledge […]