Ebola

Ebola vaccine developed in Canada shows promising results

A phase 1 randomized controlled trial has found an Ebola virus disease (EVD) vaccine, developed in Canada, was well-tolerated with no safety concerns, and high antibodies were present in participants 6 months after immunization. The study, led by Canadian researchers, is published in CMAJ (Canadian Medical Association Journal). The research team conducted the clinical trial […]

Ebola

Lessons from Ebola: New approach improves disease outbreak management

A new approach to information gathering could allow scientists to quickly identify the most effective way to manage a disease outbreak, an advance that could save lives. Developed by an international team of researchers led by Penn State scientists using insights from the 2014 Ebola outbreak, the method pinpoints critical pieces of missing information required […]

Ebola Infectious Diseases / Bacteria / Viruses

New animal infectious disease modeling study has implications for humans

A new study published in the Proceedings of the National Academy of Sciences, will help answer a fundamental disease ecology question about the spread of infectious diseases such as Ebola and rabies through communities in human and animal populations. The study, led by Georgetown University Assistant Professor of Biology Shweta Bansal, Georgetown Ph.D. candidate Pratha […]

Ebola

Ebola vaccines provide immune responses after 1 year

Immune responses to Ebola vaccines at one year after vaccination are examined in a new study appearing in JAMA. The Ebola virus vaccine strategies evaluated by the World Health Organization in response to the 2014-2016 outbreak in West Africa included a heterologous primary and booster vaccination schedule of the adenovirus type 26 vector vaccine encoding […]

Ebola

Disease “superspreaders” were driving cause of 2014 Ebola epidemic

A new study about the overwhelming importance of “superspreaders” in some infectious disease epidemics has shown that in the catastrophic 2014-15 Ebola epidemic in West Africa, about 3 percent of the people infected were ultimately responsible for infecting 61 percent of all cases. The issue of superspreaders is so significant, scientists say, that it’s important […]

Ebola

New scoring system predicts Ebola severity

While Ebola virus disease (EVD) is notorious for being one of the world’s most deadly infections, it actually has a wide range of outcomes, where asymptomatic presentation may be as common as fatality. Now, researchers have developed a new scale, described in PLOS Neglected Tropical Diseases, which can help predict which patients are most at […]