Huntington's Disease

Could fasting help to treat Huntington’s disease?

Restricting food intake to a specific time period each day could benefit people living with Huntington’s disease, a new study indicates. Restricting food intake to the same 6-hour period was found to benefit mouse models of Huntington’s disease. Having studied mouse models of the disease, researchers found that a strict eating schedule — which involved […]

Huntington's Disease Nutrition / Diet

Neurodegenerative disease: Restricting eating times may boost life quality

Eating meals at the same time each day may be an effective way to improve quality of life for individuals with neurodegenerative disorders, a new study suggests. Researchers suggest that restricting eating times may benefit people with Huntington’s disease and other neurodegenerative disorders. In a study conducted on mice with Huntington’s disease, researchers discovered that […]

Huntington's Disease

Human enzyme may be key to unraveling Alzheimer’s disease

Protein aggregates are the hallmark of a number of neurodegenerative diseases. New research, published in the journal PLOS Biology, examines a human enzyme that unravels these disruptive plaques. Abnormal protein buildups (shown here) are involved in a number of neurodegenerative conditions, including Alzheimer’s disease. Neurodegenerative diseases already affect millions of people in the […]

Huntington's Disease

Blood test can predict onset and track progression of Huntington’s disease

The first blood test that can predict the onset and progression of Huntington’s disease has been identified by a UCL-led study. The researchers say their findings, published in Lancet Neurology, should help test new treatments for the genetic brain disorder, which is fatal and currently incurable. “This is the first time a potential blood biomarker […]

Huntington's Disease

Study uncovers a mechanism driving cognitive symptoms in Huntington’s disease

Individuals affected by Huntington’s disease (HD) inherit a mutation in the Huntingtin gene (HTT) that causes the encoded HTT protein to misfold and accumulate in neurons. This accumulation causes motor neuron degeneration, leading to the motor symptoms of the disease, including tremor and loss of muscle coordination. However, less is known about how the mutant […]

Huntington's Disease

New discovery is a step towards developing Huntington’s disease treatments before symptoms appear

Early warning signs of Huntington’s disease have been uncovered in a sheep carrying the human HD mutation, leading the way for new insight into this devastating illness, a new study in Scientific Reports has found. Researchers from the University of Surrey and University of Cambridge have identified early biomarkers of Huntington’s disease during examinations of […]

Huntington's Disease

Stanford study identifies new biomarkers for Huntington’s disease

Researchers at Stanford University School of Medicine have identified several new biological markers to measure the progression of the inherited neurodegenerative disorder Huntington’s disease (HD). Their findings, which will be published online in The Journal of Experimental Medicine, could benefit clinical trials that test new treatments for the disease. In HD, an […]