Restricting food intake to a specific time period each day could benefit people living with Huntington’s disease, a new study indicates. Restricting food intake to the same 6-hour period was found to benefit mouse models of Huntington’s disease. Having studied mouse models of the disease, researchers found that a strict eating schedule — which involved […]
Eating meals at the same time each day may be an effective way to improve quality of life for individuals with neurodegenerative disorders, a new study suggests. Researchers suggest that restricting eating times may benefit people with Huntington’s disease and other neurodegenerative disorders. In a study conducted on mice with Huntington’s disease, researchers discovered that […]
Protein aggregates are the hallmark of a number of neurodegenerative diseases. New research, published in the journal PLOS Biology, examines a human enzyme that unravels these disruptive plaques. Abnormal protein buildups (shown here) are involved in a number of neurodegenerative conditions, including Alzheimer’s disease. Neurodegenerative diseases already affect millions of people in the […]
Research, published this week in the Journal of Clinical Investigation, offers hope for people with Huntington’s disease. Gene editing could be the key to an eventual cure. Gene editing advancements could produce a future cure for Huntington’s disease. Huntington’s disease, an inherited condition, causes the progressive degeneration of nerve cells in the […]
The first blood test that can predict the onset and progression of Huntington’s disease has been identified by a UCL-led study. The researchers say their findings, published in Lancet Neurology, should help test new treatments for the genetic brain disorder, which is fatal and currently incurable. “This is the first time a potential blood biomarker […]
Individuals affected by Huntington’s disease (HD) inherit a mutation in the Huntingtin gene (HTT) that causes the encoded HTT protein to misfold and accumulate in neurons. This accumulation causes motor neuron degeneration, leading to the motor symptoms of the disease, including tremor and loss of muscle coordination. However, less is known about how the mutant […]
Early warning signs of Huntington’s disease have been uncovered in a sheep carrying the human HD mutation, leading the way for new insight into this devastating illness, a new study in Scientific Reports has found. Researchers from the University of Surrey and University of Cambridge have identified early biomarkers of Huntington’s disease during examinations of […]
For many years, research on neurodegenerative diseases and spinal cord and brain injury has focused on damage to nerve cells, or neurons. Now, a new study of astrocytes – a type of cell that surrounds and supports neurons – finds that there is a subtype that can turn rogue and kill neurons, instead of helping […]
New research on mice finds Huntington’s disease – a hereditary, progressive disorder involving death of nerve cells in the brain – may also concern defects in skeletal muscle tissue. The finding could lead to better treatments for improving motor function, and it may also offer biomarkers for monitoring the disease without having to examine the […]
Researchers at Stanford University School of Medicine have identified several new biological markers to measure the progression of the inherited neurodegenerative disorder Huntington’s disease (HD). Their findings, which will be published online in The Journal of Experimental Medicine, could benefit clinical trials that test new treatments for the disease. In HD, an […]