Ebola

Ebola vaccine developed in Canada shows promising results

A phase 1 randomized controlled trial has found an Ebola virus disease (EVD) vaccine, developed in Canada, was well-tolerated with no safety concerns, and high antibodies were present in participants 6 months after immunization. The study, led by Canadian researchers, is published in CMAJ (Canadian Medical Association Journal). The research team conducted the […]

Ebola

Lessons from Ebola: New approach improves disease outbreak management

A new approach to information gathering could allow scientists to quickly identify the most effective way to manage a disease outbreak, an advance that could save lives. Developed by an international team of researchers led by Penn State scientists using insights from the 2014 Ebola outbreak, the method pinpoints critical pieces of missing information required […]

Ebola

Ebola vaccines provide immune responses after 1 year

Immune responses to Ebola vaccines at one year after vaccination are examined in a new study appearing in JAMA. The Ebola virus vaccine strategies evaluated by the World Health Organization in response to the 2014-2016 outbreak in West Africa included a heterologous primary and booster vaccination schedule of the adenovirus type 26 […]

Ebola

New scoring system predicts Ebola severity

While Ebola virus disease (EVD) is notorious for being one of the world’s most deadly infections, it actually has a wide range of outcomes, where asymptomatic presentation may be as common as fatality. Now, researchers have developed a new scale, described in PLOS Neglected Tropical Diseases, which can help predict which patients are most […]

Ebola

Symptom-free Ebola infections detected in West Africa

Between 2013 and 2016, tens of thousands of people in West Africa contracted Ebola virus disease, making the epidemic the largest and longest on record. But the number of reported cases – roughly 28,000 – may be an underestimate of the total number of people infected, since it includes only people who showed symptoms […]